Energy Requirement for Caspase Activation and Neuronal Cell Death
نویسندگان
چکیده
منابع مشابه
Energy requirement for caspase activation and neuronal cell death.
Recent work has shown that execution of the apoptotic program involves a relatively limited number of pathways. According to a general view, these would converge to activate the caspase family of proteases. However, there is increasing evidence that apoptotic-like features can be found also when cells are treated with inhibitors of caspases as the cell permeable tripeptide, Z-Val-Ala-Asp-fluoro...
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Caspase-mediated apoptosis is the death program of choice in many developmental and physiologic settings (Kerr et al., 1972; Strasser et al., 2000; Kaufmann and Hengartner, 2001). It would, however, be very dangerous for the organism to depend on a single protease family for clearance of unwanted and potentially dangerous cells. Indeed, the exclusive role of caspases in the execution of program...
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ژورنال
عنوان ژورنال: Brain Pathology
سال: 2000
ISSN: 1015-6305
DOI: 10.1111/j.1750-3639.2000.tb00261.x